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Xofigo is a radiopharmaceutical (a medicine containing a radioactive substance) that is because it used to treat adults with cancer of the prostate (a gland of the male reproductive system).

it is used when castration (to stop the production of male hormones) by surgery or with medicines does not work, and when the cancer has spread to the bones (bone metastases) and is causing symptoms such as pain, but has not spread to other internal organs. It should be used only for patients who have had at least two previous treatments for prostate cancer or who cannot receive other treatments.

 used on its own or in combination with a medicine known as an ‘LHRH analogue’. because

Xofigo contains the active substance radium-223 dichloride. and also

HOW IS XOFIGO USED ?

Xofigo can only be obtained with a prescription and should only be handled and given by someone who is authorised to use radioactive medicines and after evaluation of the patient by a qualified doctor. and because

The dose of Xofigo is calculated to provide a specific dose of radioactivity based on the patient’s body weight. The

medicine is slowly injected into a vein usually for up to one minute. Injections are repeated every 4 weeks for a total of 6 injections. and also

For more information about using Xofigo, see the package leaflet or contact your doctor or pharmacist.

SIDE EFFECTS OF XOFIGO?

The most common side effects with (which may affect more than 1 in 10 people) are diarrhoea, nausea (feeling sick),

vomiting, thrombocytopenia (low blood-platelet counts) and bone fractures. The most serious side effects were

thrombocytopenia and neutropenia (low levels of neutrophils, a type of white blood cell that fights infection). For the full

list of side effects of Xofigo, see the package leaflet.

Xofigo must not be used with the medicine abiraterone acetate and the corticosteroids prednisone or prednisolone. For the full list of restrictions, see the package leaflet.